Familial polyposis
نویسندگان
چکیده
منابع مشابه
Familial Adenomatous Polyposis.
Familial adenomatous polyposis (FAP), caused by a germline mutation in the adenomatous polyposis coli (APC) gene on chromosome 5q21, is an autosomal dominant disorder characterized by hundreds to thousands of adenomas throughout the gastrointestinal tract. A variety of extraintestinal manifestations, including thyroid, soft tissue, and brain tumors, may also be present. These patients inevitabl...
متن کاملFamilial adenomatous polyposis coli.
The other mode of treating these patients are subtotal colectomy with ileorectal anastomosis alongwith regular follow up with proctoscopy for development of cancer in retained rectal mucosa(3,7). Recently, Stevan et al. (8) utilized laproscope for total proctocolectomy as well as ileoanal anostomosis while others performed ileopouch anal anastomosis alongwith total proctocolectomy(9,10). Thus t...
متن کاملFamilial intestinal polyposis.
Familial polyposis is of interest for its own sake as a sort of pathological curiosity and also in relation to the problem of cancer. The term " polyposis " is used to describe a widespread adenomatous proliferation of the intestinal mucous membrane, leading to the formation of multiple adenomata. It should not be applied to intestinal polyps of different histological structure, such as inflamm...
متن کاملFamilial Polyposis Coli
observations which they regard as established facts. For example: in discussing patients with temporal lobe epilepsy (TLE), the statement is made, "interictal aggressiveness is a common feature but is relatively well tolerated by many of the families, probably because of the marked emotional warmth customarily displayed by these same patients toward the family members." To illustrate these poin...
متن کاملFamilial adenomatous polyposis
Familial adenomatous polyposis (FAP) is characterized by the development of many tens to thousands of adenomas in the rectum and colon during the second decade of life. FAP has an incidence at birth of about 1/8,300, it manifests equally in both sexes, and accounts for less than 1% of colorectal cancer (CRC) cases. In the European Union, prevalence has been estimated at 1/11,300-37,600. Most pa...
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ژورنال
عنوان ژورنال: Cancer
سال: 1977
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197701)39:1<267::aid-cncr2820390141>3.0.co;2-x